How the arthritic damage in your joints may be reversed by using cannabis?
The study aims to find whether cannabis-based medicine is more than just dull pain for people with arthritis. What if it could stop the harm? This is the first research that the group has funded to study treatments that are derived from medicinal cannabis.
“People who suffer from arthritis pain are seeking solutions to enhance their lives,” said Janet Yale, the CEO, and president of The Arthritis Society. “We must research to solve the myriad concerns about medicinal cannabis and its usage. We aim to provide Canadians the opportunity to make informed decisions about their treatment alternatives and provide doctors with evidence-based guidelines that can be used to make treatment suggestions for patients. This project is a crucial step towards achieving these objectives.”
Abnormally high CB2 Receptors characterize arthritic Joints.
The research draws on previous research by Chinese scientists who have discovered that not just do arthritic joints have extremely high levels of CB2 and CB2 receptors. Still, these receptors also suggest an avenue for treatment.
What is a CB2 receptor? In simple words, CB2 is a molecule inside the wall of cells. It serves as a gateway for cannabinoids into the cell. Cells use this as a way of signaling for beneficial particles to move through it during everyday activities of the body.
The body creates its endocannabinoids, which are attached to and function on cells via CB2. Cannabis-based medicine can also be able to perform the same. Researchers believe this could be why cannabis is so effective in treating ailments like Rheumatoid arthritis.
Anecdotal Evidence Supports Cannabis Can Reverse Arthritis in Joints
The thought process follows like this: If cannabis-based medicine can make use of CB2 receptors to enter the interior of cells and directly alter the activation of pain signals within joints, could the medicine help treat joint injuries while they’re there?
There are many reasons to believe this.
A study published in The journal Philosophical Transactions of the Royal Society B discovered that our body’s endocannabinoid systems release antioxidants to help repair damaged cells when stimulated by cannabinoids from outside. Anecdotal evidence, like the case of a Maine woman whose consumption of cannabis smoothies resulted in relief so great that her arthritis symptoms went away. Arthritis symptoms disappeared and provided additional reasons to explore the treatment possibilities offered by cannabis.
Furthermore, businesses are getting on board. Canadian medicinal cannabis businesses Aphria, Inc. and the Peace Naturals Project have each offered $100k to the Arthritis Society to pay for McDougall’s research. McDougall’s research. When the market is up on the latest research is a positive indication for those suffering from the disease.
McDougall’s team hopes to figure out what’s going on with the Immune Response Connection.
The fact can be said that cannabinoid receptors are essential to play a function in regulating the body’s immune system. However, it’s not entirely clear what they do. From a strictly biological standpoint, auto-immune diseases like rheumatoid arthritis and chronic conditions like osteoarthritis don’t have much logic. Why would the body attack itself or fail to fix such vital functions, like the ability to move joints? Discovering cannabinoid receptors in inflammatory areas could give a clue.
With the help of a myriad of prior research in this area, McDougall’s team is aware that cannabis-based medications directly affect CB2 receptors and reduce inflammation and pain by triggering immune responses at sites of inflammation. This implies that the body is looking for molecules to aid in reconstructing its essential components.
The next step is to determine if the changes made to the medicine cause different reactions within the body. Researchers are studying novel methods to assess how cannabinoid receptors absorb or utilize medications. This may open up a range of treatment possibilities. A lot of our knowledge is theoretical. Therefore, most physicians and patients are grateful for the effectiveness of pain treatment. The degree to which it is understood isn’t a big deal.
We are fortunate that our understanding of the body’s endocrinoid organs is increasing. We continue to dig deeper at the methods by which cannabis-based treatments can reduce inflammation and influence nerves. In addition, we’re sure to find new ways to cure it. They could allow for the repair of permanent joint injuries caused by arthritis.